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PHARMACOTHERAPEUTICS – III

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Notes updated Click on the Rose colour Titles for Notes Title of the topic Etiopathogenesis and pharmacotherapy of diseases associated with following systems/ diseases: 1.Gastrointestinal system:   Peptic ulcer disease ,  Gastro Esophageal Reflux Disease ,  Inflammatory bowel disease ,  Liver disorders - Alcoholic liver disease , Viral hepatitis including jaundice , and  Drug induced liver disorders.   2 Haematological system:   Anaemias ,  Venous thromboembolism ,  Drug induced blood disorders .  3 Nervous system:  Epilepsy ,  Parkinsonism ,  Stroke ,  Alzheimer's disease ,  4 Psychiatry disorders:  Schizophrenia ,  Affective disorders ,  Anxiety disorders ,  Sleep disorders ,  Obsessive Compulsive disorders  5 Pain management including Pain pathways, neuralgias, headaches .  6 Evidence Based Medicine Practicals:  Hospit...
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HOSPITAL PHARMACY

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Click on the Rose colour Titles for Notes 1.Hospital - its Organisation and functions     2 Hospital pharmacy-Organisation and management           a) Organizational structure-Staff, Infrastructure & work load statistics        b) Management of materials and finance                    c) Roles & responsibilities of hospital pharmacist 3 The Budget  Preparation and implementation 4 Hospital drug policy            a) Pharmacy and Therapeutic committee (PTC)        b) Hospital formulary          c) Hospital committees -  Infection committee       Research and ethical committee           d) developing therapeutic guidelines           e) Hospital pharmacy communication - Newsletter 5 Hosp...
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CLINICAL PHARMACY

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Notes updated on 16/5/2020                    Click on the Rose colour Titles for Notes 1. Definitions, development and scope of clinical pharmacy 2. Introduction to daily activities of a clinical pharmacist   a) Drug therapy monitoring (medication chart review,        clinical review, pharmacist interventions)   b.Ward round participation      c. Adverse drug reaction management   d. Drug information and poisons information        e. Medication history   f. Patient counseling   g. Drug utilisation evaluation (DUE) and review (DUR)   h. Quality assurance of clinical pharmacy services 3. Patient data analysis      The patient's case history, its structure and use in evaluation of drug therapy &                          Understanding common...
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BIOSTATISTICS & RESEARCH METHODOLOGY

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1. Research Methodology : Introduction     a)   Types of clinical study designs:   Case studies  observational studies interventional studies     b)  Designing the methodology     c)   Sample size determination and Power of a study   Determination of sample size for simple comparative experiments,  determination of sample size to obtain a confidence interval of specified width,  power of a study     d) Report writing and presentation of data 2.1 Biostatistics :     a)   Introduction             b)   Types of data distribution     c)   Measures describing the central tendency distributions :  average,  median,  mode     d) Measurement of the spread of data - range,  variation of mean,  standard deviation,  variance,  coefficient of variation,  standard error of me...
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BPPK

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Notes added   1. Biopharmaceutics :   1. Introduction to Biopharmaceutics      a. Absorption of drugs from gastrointestinal tract.      b. Drug Distribution .      c. Drug Elimination. 2. Pharmacokinetics   :      2. Introduction to Pharmacokinetics.      a. Mathematical model      b. Drug levels in blood.      c. Pharmacokinetic model      d. Compartment models      e. Pharmacokinetic study. 3. One compartment open model.           a. Intravenous Injection (Bolus)     b. Intravenous infusion. 4. Multicompartment models.          a. Two compartment open model.      b. IV bolus, IV infusion and oral administration 5. Multiple  Dosage Regimens.        a. Repititive Intravenous injections ...
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CLINICAL TOXICOLOGY

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1. General principles involved in the management of poisoning 2. Antidotes and the clinical applications. 3. Supportive care in clinical Toxicology. 4. Gut Decontamination. 5. Elimination Enhancement. 6. Toxicokinetics. 7. Clinical symptoms and management of acute poisoning with the following agents :     a) Pesticide poisoning:   organophosphorous compounds   carbamates   organochlorines              pyrethroids.      b)   Opiates overdose .     c)   Antidepressants     d) Barbiturates and benzodiazepines .     e)  Alcohol: ethanol , methanol.     f)   Paracetamol and salicylates.    g) Non-steroidal anti-inflammatory drugs.    h)  Hydrocarbons:  Petroleum products and PEG . Caustics: inorganic acids and alkali.    j)   Radiation poisoning 8.  Clinical sympto...
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